If you want to give your twitch reflexes a rest try now brain! With these types of games the muscles you train the most are brain ones. So forget about timing your jumps perfectly or checking that you have enough ammo for your favorite weapon. Relax and observe!
Think outside the box, read between the lines and always remember that your actions can have an impact on events later on. In brain everything is linked together, and only the most tenacious and the ones with the keenest eye for detail can find the solutions to these types of games.